Lance C. Pagliaro, MD, conducts research in kidney, prostate, bladder, testicular and penile cancers. Dr. Pagliaro specializes in the medical treatment of these conditions using immuno-oncology drugs and other targeted therapies.

Dr. Pagliaro is interested in how molecularly targeted drugs and immune checkpoint inhibitors can be combined for the treatment of advanced renal cell carcinoma and prostate cancer. He also studies novel drug combinations for the treatment of metastatic bladder cancer.

Dr. Pagliaro's research contributes to improved standard treatment of penile cancer with spread to lymph nodes, and patients are now frequently cured of the disease. He has developed a safe and highly effective chemotherapy treatment for patients with bladder cancer who are unable to receive the standard cisplatin-based chemotherapy. Dr. Pagliaro's studies of aggressive treatment for relapsed or high-risk germ cell tumors have made it possible to cure a higher percentage of such patients.